Medivir had been working on the discovery and development of new HCV nucleotide-based inhibitors and NS5A inhibitors (NS5A replication complex inhibitor) to enable additional potential interferon-free combinations.
However, based on an evaluation of the competitive landscape and the expected evolution of therapies for HCV infection, Medivir has decided to focus exclusively on nucleotide-based polymerase inhibitors and to discontinue its NS5A inhibitor program.
“We remain very excited about our HCV nucleotide-based inhibitor program and the opportunity to develop a compound that could play an important role in interferon-free treatment”, said Richard Bethell, EVP Discovery Research, Medivir AB. “Given the attractive attributes of the nucleotide polymerase class and the scarcity of safe and effective inhibitors, today’s decision to discontinue our NS5A program will enable us to focus our resources on our nucleotide-based polymerase program, which is best placed to deliver an effective new medication for physicians and their patients.”
